| HGNC approved symbol | MTA1 |
| HGNC ID | HGNC:7410 |
| HGNC approved name | metastasis associated 1 |
| Entrez gene ID | GeneID:9112 (SSTAR profile) |
| UniProt AC (human) | Q13330 |
| UniProt ID (human) | MTA1_HUMAN |
| Pfam domains | BAH PF01426 (5-162) ELM2 PF01448 (167-219) Myb_DNA-binding PF00249 (287-331) GATA PF00320 (393-429) MTA_R1 PF17226 (464-543) |
| MGI symbol | Mta1 |
| MGI ID | MGI:2150037 |
| UniProt AC (mouse) | Q8K4B0 |
| UniProt ID (mouse) | MTA1_MOUSE |
| HGNC gene family tag | GATAD |
| HGNC gene family description | GATA zinc finger domain containing |
| Function | Chromatin remodeling cofactor |
| Modification | # |
| PMID for information on function | PMID:9885572 |
| Protein complex | NuRD |
| Target molecule | chromatin |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:9885572 |
| Comment | One subunit of NURD was identified as MTA1, a metastasis-associated protein with a region similar to the nuclear receptor corepressor, N-CoR; and antibodies against NURD partially relieve transcriptional repression by thyroid hormone receptor. These results suggest that ATP-dependent chromatin remodeling can participate in transcriptional repression by assisting repressors in gaining access to chromatin. |
| Status of entry | # |
| Expression range: | 0.0 to 189.56 |
| Mean expression: | 36.53 ± 19.85 |
| Median expression: | 32.81 |