| HGNC approved symbol | NCOA6 |
| HGNC ID | HGNC:15936 |
| HGNC approved name | nuclear receptor coactivator 6 |
| Entrez gene ID | GeneID:23054
(SSTAR profile) |
| UniProt AC (human) | Q14686 |
| UniProt ID (human) | NCOA6_HUMAN |
| Pfam domains | NCOA6_TRADD-N PF13820 (47-182) |
| MGI symbol | Ncoa6 |
| MGI ID | MGI:1929915 |
| UniProt AC (mouse) | Q9JL19 |
| UniProt ID (mouse) | NCOA6_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write cofactor |
| Modification | Histone methylation |
| PMID for information on function | PMID:17500065 |
| Protein complex | CHD8, MLL2/3, COMPASS-like MLL3,4 |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:17500065 |
| Comment | Ectopically expressed PTIP is capable of interacting with DNA damage response proteins including 53BP1, while endogenous PTIP, and a novel protein PA1 are both components of a Set1-like histone methyltransferase (HMT) complex that also contains ASH2L, RBBP5, WDR5, hDPY-30, NCOA6, SET domain-containing HMTs MLL3 and MLL4, and substoichiometric amount of JmjC domain-containing putative histone demethylase UTX. |
| Status of entry | # |