| HGNC approved symbol | PADI2 |
| HGNC ID | HGNC:18341 |
| HGNC approved name | peptidyl arginine deiminase, type II |
| Entrez gene ID | GeneID:11240 (SSTAR profile) |
| UniProt AC (human) | Q9Y2J8 |
| UniProt ID (human) | PADI2_HUMAN |
| Pfam domains | PAD_N PF08526 (2-114) PAD_M PF08527 (115-274) PAD PF03068 (286-664) |
| MGI symbol | Padi2 |
| MGI ID | MGI:1338892 |
| UniProt AC (mouse) | Q08642 |
| UniProt ID (mouse) | PADI2_MOUSE |
| HGNC gene family tag | PADI |
| HGNC gene family description | Peptidyl arginine deiminases |
| Function | Histone modification |
| Modification | Histone citrullination |
| PMID for information on function | PMID:15087120 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H2AR, H3R, H4R |
| Product | H2ARci, H3Rci, H4Rci |
| PMID for information on target | PMID:15087120 |
| Comment | Peptidylarginine deiminases (PADs) convert arginine residues in proteins into citrullines. They are suspected to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis and possibly in regulation of gene expression through histone modification |
| Status of entry | # |
| Expression range: | 0.0 to 946.11 |
| Mean expression: | 24.37 ± 81.35 |
| Median expression: | 0.54 |