| HGNC approved symbol | PARP1 |
| HGNC ID | HGNC:270 |
| HGNC approved name | poly (ADP-ribose) polymerase 1 |
| Entrez gene ID | GeneID:142 (SSTAR profile) |
| UniProt AC (human) | P09874 |
| UniProt ID (human) | PARP1_HUMAN |
| Pfam domains | zf-PARP PF00645 (11-88, 115-198) PADR1_N PF21728 (232-290) PADR1_Zn_ribbon PF08063 (291-332) BRCT PF00533 (387-463) WGR PF05406 (554-632) PARP_reg PF02877 (662-794) PARP PF00644 (808-1007) |
| MGI symbol | Parp1 |
| MGI ID | MGI:1340806 |
| UniProt AC (mouse) | P11103 |
| UniProt ID (mouse) | PARP1_MOUSE |
| HGNC gene family tag | PARP |
| HGNC gene family description | Poly (ADP-ribose) polymerases |
| Function | Chromatin remodeling |
| Modification | # |
| PMID for information on function | PMID:20926656, PMID:17177976, PMID:17396150 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H1 |
| Product | # |
| PMID for information on target | PMID:20926656 |
| Comment | Histone H1 poly[ADP]-ribosylation = PARP1, and its loss at specific loci, may be an epigenetic mechanism involved in the reprogramming of neuronal gene expression required for memory consolidation. |
| Status of entry | # |
| Expression range: | 2.84 to 311.58 |
| Mean expression: | 62.16 ± 46.38 |
| Median expression: | 48.77 |