HGNC approved symbol | PRMT1 |
HGNC ID | HGNC:5187 |
HGNC approved name | protein arginine methyltransferase 1 |
Entrez gene ID | GeneID:3276 (SSTAR profile) |
UniProt AC (human) | Q99873 |
UniProt ID (human) | ANM1_HUMAN |
Pfam domains | Methyltransf_25 PF13649 (92-189) domain PF22528 (194-358) |
MGI symbol | Prmt1 |
MGI ID | MGI:107846 |
UniProt AC (mouse) | Q9JIF0 |
UniProt ID (mouse) | ANM1_MOUSE |
HGNC gene family tag | PRMT |
HGNC gene family description | Protein arginine methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:11387442 |
Protein complex | # |
Target molecule | histone |
Target entity | H4R3 |
Product | H4R3me1, H4R3me2a |
PMID for information on target | PMID:11387442 |
Comment | PRMT1 specifically methylates arginine 3 (Arg 3) of H4 in vitro and in vivo. Methylation of Arg 3 by PRMT1 facilitates subsequent acetylation of H4 tails by p300. |
Status of entry | # |
Expression range: | 0.0 to 98.47 |
Mean expression: | 28.23 ± 15.8 |
Median expression: | 24.99 |