| HGNC approved symbol | SUPT3H |
| HGNC ID | HGNC:11466 |
| HGNC approved name | suppressor of Ty 3 homolog (S. cerevisiae) |
| Entrez gene ID | GeneID:8464
(SSTAR profile) |
| UniProt AC (human) | O75486 |
| UniProt ID (human) | SUPT3_HUMAN |
| Pfam domains | TFIID-18kDa PF02269 (26-115) |
| MGI symbol | # |
| MGI ID | MGI:# |
| UniProt AC (mouse) | # |
| UniProt ID (mouse) | # |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write cofactor |
| Modification | Histone acetylation |
| PMID for information on function | PMID:11564863 |
| Protein complex | PCAF, SAGA, STAGA |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:11564863 |
| Comment | GCN5 is a histone acetyltransferase (HAT) originally identified in Saccharomyces cerevisiae and required for transcription of specific genes within chromatin as part of the SAGA (SPT-ADA-GCN5 acetylase) coactivator complex. Mammalian cells have two distinct GCN5 homologs (PCAF and GCN5L) that have been found in three different SAGA-like complexes (PCAF complex, TFTC [TATA-binding-protein-free TAFII-containing complex], and STAGA [SPT3-TAFII31-GCN5L acetylase]). |
| Status of entry | # |